"USDOT" is an acronym for the United States Department of Transportation, one of the cabinet-level departments of the executive branch of the United States federal government. It mission is to "[s]erve the United States by ensuring a fast, safe, efficient, accessible and convenient transportation system that meets our vital national interests and enhances the quality of life of the American people, today and into the future."
The USDOT also sometimes uses the acronym "DOT" as state departments of transportation do in some contexts where the particular agency involved is clear.
How It's Used
"But the freeway system is being transformed. We have the largest carpooling network in the nation, approximately 500 miles. L.A. has been a leader in that. We're now taking it one step further. Carpools will still be able to use dedicated lanes on the freeway. But for those who aren't in a carpool and want to opt in, they can pay a price to enter the lane and be assured that they'll get 45 mph travel on the freeway. And we've got a major USDOT grant to change a couple of our freeways to demonstrate that these express lanes can work."
—John Fisher, Assistant General Manager, the Los Angeles Department of Transportation, in Suzanne Merkelson, "King of the Road," The Atlantic, June 1, 2010.